Centrifuge vessel with coaxial waste chamber having cap to prevent waste fluid transfer from the chamber into the vessel
US5244635A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 19, 1992 |
| Grant date | Sep 14, 1993 |
| Priority date | — |
| Expiry date | Jun 19, 2012 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L2400/0409
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A centrifuge vessel for performing immunoassays, affinity chromatography, and like experiments includes a center tube and an outer waste chamber. A biomaterial is held within the center tube and is capable of binding specific analytes in test samples. In operation the centrifuge vessel is rotated at high speed about its longitudinal axis, thereby causing all fluid within the center tube to be transported into the outer waste chamber while the analyte of interest remains bound to the biomaterial positioned within the center tube In the centrifuge vessel, a cap connected to the outer waste chamber and extending over the center tube includes structure for preventing waste fluid expelled to the waste chamber from re-entering the center tube. In a first embodiment, the cap is either constructed from or the inside surface is coated with a hydrophobic material which repels fluids back into the waste chamber. In a second embodiment, the cap includes a dam which allows fluid to pass into the waste chamber but blocks the migration of waste fluid back to the center tube. In a third embodiment, the cap includes a sponge that allows fluids in the center tube influenced by the intense centrifuga…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.