Patent · US Expired

Carbocyclic adenosine analogs useful as immunosuppressants

US5244896A · kind A · utility

34Cited by
4References
3Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 23, 1992
Grant dateSep 14, 1993
Priority date
Expiry dateJan 23, 2012

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D487/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

This invention relates to novel carbocyclic adenosine compounds of the formula (1) ##STR1## wherein the hydroxy substituent on the cyclopentanyl ring is in the CIS configuration relative to the bicyclic substituent, PA1 Y.sub.3, Y.sub.7, Y.sub.8 and Y.sub.9 are each independently nitrogen or a CH group, PA1 Q is NH.sub.2, halogen or hydrogen, and PA1 Z is hydrogen, halogen, or NH.sub.2 ; or a pharmaceutically-acceptable salt thereof, and to their use as immunosuppressants.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.