Patent · US Expired

Pt(IV) complexes as anti-tumor agents

US5244919A · kind A · utility

19Cited by
1References
2Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 1, 1991
Grant dateSep 14, 1993
Priority date
Expiry dateJul 1, 2011

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07F15/0093
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A Pt(IV) complex of the formula ##STR1## wherein A and A' are NH.sub.3 or an amino group; R and R.sup.1 are hydrogen, alkyl, alkenyl, aryl, aralkyl, alkylamino or alkoxy or functionalized derivatives thereof; and X is halogen or alkyl mono- or dicarboxylate. The complexes have high antitumor activity, particularly when administered orally.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.