Vascular prosthesis and method
US5246451A · kind A · utility
171Cited by
12References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 30, 1991 |
| Grant date | Sep 21, 1993 |
| Priority date | — |
| Expiry date | Apr 30, 2011 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S623/921
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A vascular graft with improved endothelial cell adhesion can be achieved on a fluoropolymer surface of a vascular graft by treating the fluoropolymer with a plasma in the presence of a non-polymerizing gas capable of providing the fluoropolymer with anionic groups and binding a protein to the treated fluoropolymer. In a preferred embodiment, the fluoropolymer surface is a plasma deposited fluoropolymer. Also in a preferred embodiment, autologous endothelial cells are seeded onto the vascular graft prior to implantation of the vascular graft in the human body.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.