Platelet-aggregating inhibitory agents from leech saliva and pharmaceutical preparations containing the same
US5246715A · kind A · utility
30Cited by
0References
10Claims
0Family size
Assignee
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Key dates
| Filing date | Jun 20, 1989 |
| Grant date | Sep 21, 1993 |
| Priority date | — |
| Expiry date | Jun 20, 2009 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/855
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A composition of matter useful as an inhibitor of blood platelet aggregation, for the treatment of various clinical disorders such as thrombotic, inflammatory and immunological disorders. This composition of matter is derived from the saliva of leeches of the Hirudinidae family. The composition contains various components, all having molecular weights lower than 2,000 daltons. The composition has an inhibitory activity against platelet aggregation induced by various aggregating agents, including Platelet Activating Factor-acether (PAF-acether), arachidonic acid, thrombin, ADP and epinephrine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.