2-aminopyrimidine-4-carboxamide derivatives, their preparation and their use in therapeutics
US5246939A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 26, 1992 |
| Grant date | Sep 21, 1993 |
| Priority date | — |
| Expiry date | Jun 26, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P15/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A compound which is a 2-aminopyrimidine carboxamide derivative represented by formula (I) ##STR1## in which X represents hydrogen, fluorine, chlorine, methyl, 1-methylethyl or methoxy, with the proviso that more than one substituent X may be present in which case each X may be the same or different, PA0 n represents 2 or 3, PA0 m represents 1, in which case p represents 1, or else PA0 m represents 0, in which case p represents 2, PA0 q represents 0 or 1, and PA0 R.sub.1 represents a hydrogen atom; or a pharmaceutically acceptable acid addition salt thereof. A compound of formula (I) has .alpha..sub.1 -adrenergic receptor antagonist activity and is useful as a therapeutic substance.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.