Substituted alkenoic acid and its derivatives

US5246966A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Heinrich Meier · Wuppertal, DE
• John E. B. Ransohoff · Wuppertal, DE
• Trevor S. Abram · Marlow, GB
• Peter Norman · Warwick, GB

Key dates

• Filing date: Dec 30, 1991
• Grant date: Sep 21, 1993
• Expiry date: Dec 30, 2011

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C323/62
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The new substituted alkenoic acid derivatives can be prepared by reacting the appropriate aldehyde with a phosphonium compound. The compounds have leukotriene antagonistic properties and can be incorporated into pharmaceutical compositions.