Process for the production of sclareolide

US5247100A · kind A · utility

Assignee

• Henkel Kommanditgesellschaft auf Aktien · DE

Inventors

• Thomas Gerke · Goldkronach, DE
• Klaus Bruns · Uerdingen, DE

Key dates

• Filing date: Jun 22, 1992
• Grant date: Sep 21, 1993
• Expiry date: Jun 22, 2012

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D307/92
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process for the production of sclareolide from sclareol comprising the steps of PA0 A) oxidatively degrading sclareol to a reaction product which is one or both of the following compounds: ##STR1## using either a hypochlorite salt in the presence of a ruthenium salt or potassium permanganate, and PA0 B) oxidizing the above reaction product with a peracid or salt thereof to form sclareolide. The above process results in good yields and much shorter reaction times than prior art processes.