Patent · US Expired

Oral osmotic device with hydrogel driving member

US5248310A · kind A · utility

18Cited by
31References
28Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 27, 1992
Grant dateSep 28, 1993
Priority date
Expiry dateMar 27, 2012

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K9/0004
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

An osmotic device (10) for delivering a beneficial drug, such as an anti-fungal, into the mouth of a human patient is disclosed. The device (10) has a size and shape adapting it to be comfortably retained in the mouth for extended periods of time. The device (10) comprises a wall (12) surrounding a compartment (13) housing a layer of an agent (14) that is insoluble to very soluble in aqueous biological fluids, e.g., saliva, and a layer (16) of a fluid swellable, hydrophilic polymer. A passageway (17) in the wall (12) connects the agent (14) with the exterior of the device (10). The wall (12) is permeable to the passage of aqueous biological fluid but substantially impermeable to the passage of the hydrophilic polymer (16). In one embodiment the beneficial agent (14) has a different color than the hydrophilic polymer (16). The wall (12) is sufficiently translucent to permit the patient to see the amount of drug/beneficial agent (14) remaining to be delivered. Marking lines (19) may be provided on the wall (12) indicating the amount of drug/agent (14) which has been delivered and/or the amount remaining to be delivered.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.