Hypertonic isochloremic formulation for circulatory shock
US5248507A · kind A · utility
5Cited by
4References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 31, 1991 |
| Grant date | Sep 28, 1993 |
| Priority date | — |
| Expiry date | May 31, 2011 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P3/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a hypertonic crystalloid resuscitation fluid particularly useful in treating circulatory shock arising from loss of blood. A pharmaceutical formulation prepared from sodium chloride in a range of about 2-7 osmolar parts and sodium acetate in a range of about 1-2 osmolar parts where the total osmolar concentration exceeds 500 mOsm can be used as a small volume rapid bolus resuscitation fluid which has little effect on plasma chloride levels. Blood flow is improved while arterial pressure is improved to the point of sustaining oxygen supply to tissues and organs in the recumbent recipient.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.