Methods and compositions for treatment of cancer using oligonucleotides
US5248671A · kind A · utility
58Cited by
9References
19Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Dec 9, 1991 |
| Grant date | Sep 28, 1993 |
| Priority date | — |
| Expiry date | Dec 9, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/1135
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides methods useful in autologous bone marrow transplantation and cancer therapy. According to one aspect of the invention, bone marrow cells from a patient having cancer are treated with selected antisense oligonucleotides in order to deplete the bone marrow of malignant cells prior to infusion back into the bone marrow donor. In a separate embodiment, selected antisense oligonucleotides are administered systemically for anticancer therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.