Pyrrolo(2,3-d)pyrimidines

US5248775A · kind A · utility

Assignee

• THE TRUSTEES OF PRINCETON UNIVERSITY · US

Inventors

• Edward C. Taylor · Princeton, US
• Dietmar Kuhnt · Burscheid, DE
• Chuan Shih · Carmel, US
• Gerald B. Grindey · Indianapolis, US

Key dates

• Filing date: Jan 31, 1992
• Grant date: Sep 28, 1993
• Expiry date: Jan 31, 2012

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02P20/582
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

3-Ethynylpyrrolo[2,3-d]pyrimidines are chemical intermediates for antineoplastic N-(acyl)glutamic acid derivatives. A typical embodiment is 3-ethynyl-4-hydroxy-6-pivaloylaminopyrrolo[2,3-d]pyrimidine.