Triterpene derivatives
US5248807A · kind A · utility
44Cited by
0References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 8, 1992 |
| Grant date | Sep 28, 1993 |
| Priority date | — |
| Expiry date | Jul 8, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J63/008
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides triterpene derivatives of the following formula: ##STR1## wherein, R.sup.1 is hydrogen or metabolic ester-residue; R.sup.3 is optionally substituted aryl or optionally substituted aromatic heterocycle; X is hydrogen and Y is hydroxy or X and Y may form together oxo; Z is an oxygen or two hydrogen atoms, or the salts thereof, which have anti-endothelin activities and are useful for preventing or treating cardiovascular failure, and pharmaceutical compositions thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.