Biotransformation process for the production of invermectin derivatives
US5250422A · kind A · utility
2Cited by
7References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 11, 1992 |
| Grant date | Oct 5, 1993 |
| Priority date | — |
| Expiry date | May 11, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P19/623
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Incubation of 13.beta.-hydroxy ivermectin aglycone with a species of Bacillus subtilis or the incubation of 13-deoxy ivermectin aglycone with a mixed culture of a species of Bacillus subtilis and of Streptomyces griseus results in the production of 13-.beta. ivermectin monoglucopyranoside as the major product and of 5-.beta. ivermectin monoglucopyranoside as the minor product.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.