Inhibitors of HIV protease
US5250563A · kind A · utility
10Cited by
2References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 25, 1992 |
| Grant date | Oct 5, 1993 |
| Priority date | — |
| Expiry date | Sep 25, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D209/54
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel cytochalasins are the biotransformed products after incubation with a substrate in a culture of the microorganism Kibdelosporangium sp. (Merck Culture Collection MA 6559), ATCC No. 53771. The compounds of the present invention inhibit HIV protease and are useful in the prevention or treatment of infection by HIV and the treatment of AIDS, either as a compound, pharmaceutically acceptable salt, pharmaceutical composition ingredient, whether or not as a prodrug or as a combination with other antivirals, anti-infectives, immunomodulators, antibiotics or vaccines.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.