Method of intercoversion of enantiomers of acyclic 1,2-dihydroxy-3-alkenes
US5250743A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Dec 31, 1992 |
| Grant date | Oct 5, 1993 |
| Priority date | — |
| Expiry date | Dec 31, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/09
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
In accordance with the present invention, a method for the interconvertion of the enantiomers of acyclic 1,2-dihydroxy-3-alkenes or for converting either enantiomer of acylic 1,2-dihydroxy-3-alkenes to the corresponding antipodal 1-hydroxy-2-alkoxy-3-alkene compounds has been discovered, comprising reacting in an acidic reaction media either enantiomer of an acylic vinyl epoxide (which can be derived from the corresponding acyclic 1,2-dihydroxy-3-alkene) with water, alcohol, or a mixture thereof. When substantially optically pure acyclic vinyl epoxide compounds are employed in the inventive method, the interconverted acyclic 1,2-dihydroxy-3-alkene or 1-hydroxy-2-alkoxy-3-alkene compound products are also substantially optically pure.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.