Avian erythroblastosis virus vectors for integration and expression of heterologous genes in avian cells
US5252465A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 25, 1990 |
| Grant date | Oct 12, 1993 |
| Priority date | — |
| Expiry date | Jun 25, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/11043
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A viral vector for the integration and expression of at least one heterologous gene in fowl pest cells consists wholly or in part of the proviral genome of fowl pest erythroblastosis or of a related virus in which said heterologous gene(s) replace(s) the v-erbA gene and/or the v-erB gene. Said gene(s) is(are) controlled either by an LTR promoter of the same virus, in which case the heterologous gene(s); mimics(s) the gene(s) it(they) replace, or by a heterologous promoter, in which case the additional att sequence is situated upstream of said heterologous promoter.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.