Preparation of 4-hydroxymethyltetrahydropyrans

US5252755A · kind A · utility

Assignee

• BASF SE

Inventors

• Jochem Henkelmann · Mannheim, DE
• Thomas Ruehl · Bischofswerda, DE
• Horst Zimmermann · Mannheim, DE
• Norbert Goetz
• Wolfgang Spiegler · Worms, DE
• Thomas Kuekenhoehner · Bischofswerda, DE

Key dates

• Filing date: Dec 14, 1992
• Grant date: Oct 12, 1993
• Expiry date: Dec 14, 2012

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D309/06
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process for the preparation of 4-hydroxymethyltetrahydropyrans of the formula I ##STR1## where R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are hydrogen, C.sub.1 - to C.sub.12 -alkyl, C.sub.3 - to C.sub.8 -cycloalkyl, aryl or C.sub.7 - to C.sub.20 -aralkyl, comprises reacting a tetrahydropyrancarboxylic ester of the formula II ##STR2## where R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are as defined above, and R.sup.5 is hydrogen or C.sub.1 - to C.sub.12 -alkyl, at from 50.degree. to 400.degree. C. and at from 1 to 400 bar in the presence of hydrogen and a hydrogenation catalyst.