Site-specific modification of the candida tropicals genome
US5254466A · kind A · utility
41Cited by
1References
30Claims
0Family size
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Key dates
| Filing date | Nov 6, 1989 |
| Grant date | Oct 19, 1993 |
| Priority date | — |
| Expiry date | Nov 6, 2009 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/924
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The POX genes of C. tropicalis are disrupted resulting in the complete blockage of the beta-oxidation pathway in the strain. Fermentation of C. tropicalis cells having disrupted genes on alkane, fatty acid and fatty acid ester substrates produces substantially pure dicarboxylic acids in substantially quantitative yield.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.