Composition and treatment with biologically active peptides and antibiotic
US5254535A · kind A · utility
13Cited by
6References
77Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 5, 1989 |
| Grant date | Oct 19, 1993 |
| Priority date | — |
| Expiry date | Sep 5, 2009 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A composition comprising at least one biologically active amphiphilic peptide, said peptide being an ion channel-forming peptide, and an antibiotic selected from the class consiting of bacitracins, aminoglycosides, penicillins, monobactams, hydrophobic antibiotics, 50-S ribosome inhibitors, antibiotics having a large lipid like lactone ring, and derivatives or analogues thereof. The biologically active amphiphilic peptide and the antibiotic may be administered in amounts effective to inhibit growth of a target cell. The biologically active amphiphilic peptide and antibiotic may potentiate each other.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.