Acyl derivative of dianhydrohexitols
US5254570A · kind A · utility
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6Claims
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Key dates
| Filing date | Sep 20, 1989 |
| Grant date | Oct 19, 1993 |
| Priority date | — |
| Expiry date | Sep 20, 2009 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a pharmaceutical composition comprising: (a) a compound of the formula ##STR1## wherein R.sup.1 and R.sup.2 are as defined below; and (b) isosorbide 5-mononitrate or isosorbide 2-mononitrate or glycerol trinitrate or glycerol 1-mononitrate or glycerol 2-mononitrate: and, optionally (c) a pharmaceutically acceptable carrier. The composition is useful in the prevention and treatment of cardiovascular diseases, and is especially useful in the prevention and treatment of angina pectoris and myocardial infarction.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.