Patent · US Expired

Ribozymes

US5254678A · kind A · utility

118Cited by

1References

7Claims

0Family size

Assignee

Gene Shears Pty. Limited · AU

Inventors

James Haseloff · Cambridge, US
Wayne Gerlach · Acacia Hills, AU
Philip Anthony Jennings · Chatswood, AU
Fiona Helen Cameron · South Canberra, AU

Key dates

Filing date	Aug 5, 1992
Grant date	Oct 19, 1993
Priority date	—
Expiry date	Aug 5, 2012

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2310/124
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Compounds having highly specific endoribonuclease activity are described. The compounds of this invention, also known as ribozymes, comprise ribonucleotides having two hybridizing regions with predetermined sequences capable of hybridizing with a target RNA, a region of defined sequence and a base paired stem region.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.