Liquid sample/reagent metering and delivery method
US5255568A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 22, 1992 |
| Grant date | Oct 26, 1993 |
| Priority date | — |
| Expiry date | Oct 22, 2012 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/2575
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method for sampling, metering and delivering precise microliter volume aliquots of a liquid blood sample to mixing and testing means of an electronic blood analysis system for analysis using a sampling and metering valve assembly in which is defined plural through fluid flow paths, one of the flow paths including a loop for metering and isolating a sample aliquot therein, the method comprising the steps of defining first and second dedicated passages within the valve assembly displaced one from the other and from the loop containing the isolated aliquot, introducing an inert gas to the loop to force the aliquot therein to said first dedicated passage at the displaced location thereof, placing the first and second dedicated passages in communicating relationship and introducing lyse reagent to the second dedicated passage to force the isolated aliquot from the first dedicated passage with the lyse reagent to a location exterior of the valve assembly without contaminating any flow paths which has been traversed by the liquid sample or a fluid other than the lyse reagent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.