3-hydroxy-pyridin-4-ones useful for treating parasitic infections
US5256676A · kind A · utility
54Cited by
1References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 24, 1992 |
| Grant date | Oct 26, 1993 |
| Priority date | — |
| Expiry date | Jul 24, 2012 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
3-Hydroxypyridin-4-ones of formula (I) ##STR1## in which R.sub.1 is a C.sub.3 or C.sub.4 hydroxyalkyl group in which the hydroxy group is terminally substituted on the alkyl group, R.sub.2 is methyl or ethyl and R.sub.3 and R.sub.4 are each separately hydrogen, methyl or ethyl but with the proviso that the total number of carbon atoms in R.sub.1 to R.sub.4 is no more than six, the compound optionally being in the form of a physiologically acceptable salt and/or pro-drug thereof, are of value for the treatment of conditions caused by iron dependent parasites, particularly malaria.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.