Patent · US Expired

Process for the preparation of (2R,3R)-cis)-.beta.-phenylglycidic acid

US5256803A · kind A · utility

4Cited by
1References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 21, 1992
Grant dateOct 26, 1993
Priority date
Expiry dateAug 21, 2012

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D303/48
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A method for preparing .beta.-phenylglycidic-(2R, 3R) acid optionally in the form of salt or ester by precipitation of the salt of the .beta.-phenylglycidic-(2R,3R) acid with (+)-.alpha.-methylbenzylamine-(R) in a solution of a mixture of salts of cis and trans .beta.-phenylglycidic acids with (+)-.alpha.-methylbenzylamine(R)- and the use of the resulting product for preparing taxol and its analogs.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.