Process for the detection or determination of oxygen by EPR spectrometry using radical lithium phthalocyanines and composition usable for in vivo determination
US5258313A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jun 28, 1991 |
| Grant date | Nov 2, 1993 |
| Priority date | — |
| Expiry date | Jun 28, 2011 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/24
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a process for the detection or determination of molecular oxygen by EPR spectrometry using radical lithium phthalocyanines and a composition usable for in vivo determination. In the process, a medium is contacted with a radical lithium phthalocyanine in accordance with the formula: ##STR1## in which R.sup.2, R.sup.3, R.sup.6, R.sup.7, R.sup.10, R.sup.11, R.sup.14 and R.sup.15 represent an alkyl or an alkoxy radical group with 1-3 carbon atoms and R.sup.1, R.sup.4, R.sup.5, R.sup.8, R.sup.9, R.sup.12, R.sup.13 and R.sup.16 represent a hydrogen or deuterium atom, and the EPR signal of the radical lithium phthalocyanine in contact with the medium is examined.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.