Patent · US Expired

2-spirocyclopropyl 4-acylcephems

US5258377A · kind A · utility

9Cited by
4References
13Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 8, 1991
Grant dateNov 2, 1993
Priority date
Expiry dateApr 8, 2011

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P29/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Derivatives of 2-spirocyclopropyl 4-acylcephem sulfones of the formula (I) ##STR1## are provided which are useful as potent elastase inhibitors and hence are useful in the prevention, control and treatment of inflammatory conditions, especially arthritis and emphysema.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.