Patent · US Expired

Cholesterol lowering compounds

US5258401A · kind A · utility

10Cited by
5References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 10, 1992
Grant dateNov 2, 1993
Priority date
Expiry dateSep 10, 2012

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D493/08
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Disclosed herein are compounds of structural formula (I) ##STR1## which are useful as cholesterol lowering agents. These compounds are also useful as inhibitors of squalene synthase, inhibitors of fungal growth, inhibitors of farnesyl-protein transferase and farnesylation of the oncogene protein Ras. These compounds are also useful in the treatment of cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.