Cryogenic probe for NMR microscopy
US5258710A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 27, 1992 |
| Grant date | Nov 2, 1993 |
| Priority date | — |
| Expiry date | Mar 27, 2012 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01R33/3403
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An apparatus for microscopic imaging employing nuclear magnetic resonance is constructed from a cryogenic probe which is situated in a conventional magnetic resonance imaging system. The cryogenic probe employs a number of chambers and cryogenic liquids which cool a superconductor resonator to very low temperatures. A sample tube for containing a small specimen is heated to a temperature above its freezing point by flowing nitrogen gas over the specimen. A secondary resonant circuit is inductively coupled to the superconducting resonator. A transceiver passes RF signals to be transmitted into the specimen through the secondary resonant circuit causing the superconducting resonator to transmit the RF signal into the specimen. The resonator then acts as a receive coil and receives a signal from the specimen which is inductively passed to the secondary resonator circuit from which an image is generated. The use of superconductors having low resistance and low temperatures causes noise to be significantly reduced, and the signal-to-noise ratio to be substantially increased.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.