Process of making Langmuir-Blodgett films having photo-electronic properties
US5260004A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Dec 2, 1991 |
| Grant date | Nov 9, 1993 |
| Priority date | — |
| Expiry date | Dec 2, 2011 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB29K2089/00
- WIPO fieldMicro-structural and nano-technology
- WIPO sectorChemistry
Abstract
Langmuir-Blodgett films having photo-electronic properties and methods of making the same. The instant films may be made, for example, by spreading a mixture of one or more types of biotinylated lipids and one or more types of electrically-conductive lipids over a water-miscible liquid subphase. Conjugated molecules comprising a biotin-binding component made up of an avidin or streptavidin molecule or a fragment or derivative thereof having biotin-binding activity and a photodynamic proteinaceous component are then injected into the subphase. Because of the affinity between biotin and the biotin-binding component, the conjugated molecules bind to the biotinylated lipids. The air-subphase interface is then compressed, causing the biotinylated lipids and electrically-conductive lipids to form a monolayer thereat. In one embodiment, the biotin-binding component has biotin-binding sites available on its underside which may be used to bind biotinylated derivatives of one or more different species of photodynamic proteinaceous components and/or to build up a multilayered complex of biotin-binding molecules and functional proteinaceous components using biotinylated rigid or flexible coupl…
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