Stabilized enzymatic antimicrobial compositions
US5262151A · kind A · utility
Inventor
Key dates
| Filing date | Aug 24, 1992 |
| Grant date | Nov 16, 1993 |
| Priority date | — |
| Expiry date | Aug 24, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61Q11/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A stabilized aqueous composition capable of producing or, in the presence of saliva or other humoral fluid, leading to the production of antimicrobially effective concentrations of hypothiocyanite ions (OSCN--) are herein described. The composition contains an oxidoreductase enzyme and its specific substrate, for the purpose of producing hydrogen peroxide of at least the minimum effective concentration, and in addition, catalase for the destruction of hydrogen peroxide to prevent premature oxidoreductase enzyme decomposition. Optionally, a peroxidase enzyme may be included to act upon the aforementioned hydrogen peroxide, thereby oxidizing thiocyanate ions to produce the antimicrobial concentrations of hypothiocyanite ions (OSCN--).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.