Specific binding analytical and separation methods using carboxy containing polymers

US5262297A · kind A · utility

Assignee

• EASTMAN KODAK COMPANY · US

Inventors

• Richard C. Sutton · Rochester, US
• Susan J. Danielson · Rochester, US
• John B. Findlay · Rochester, US
• Fred. T. Oakes · Rochester, US
• Marsha D. B. Oenick · Rochester, US
• Ignazio S. Ponticello · Pittsford, US
• Harold C. Warren, III · Rush, US

Key dates

• Filing date: Apr 30, 1992
• Grant date: Nov 16, 1993
• Expiry date: Apr 30, 2012

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S436/824
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Specific binding methods are used for diagnostic assays and purification separations whereby the specific binding capture reagent is prepared from copolymers having highly reactive carboxy groups. These groups are extended from the polymer surface with a linking group having from 8 to 50 atoms in the chain and two or more alkylene, arylene, alkylenearylene or arylenealkylene groups. To these reactive groups is attached a biologically active substance such as a protein or oligonucleotide which then participates in the diagnostic assays or purification separation methods.