Patent · US Expired

Method for obtaining bone marrow free of tumor cells using transforming growth factor .beta.3

US5262319A · kind A · utility

31Cited by
0References
1Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 25, 1990
Grant dateNov 16, 1993
Priority date
Expiry dateJun 25, 2010

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2333/495
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides (1) an antibody which (a) specifically binds to human TGF-.beta.3 and (b) exhibits substantially no cross reactivity with TGF-.beta.1 or TGF-.beta.2 and (2) antibodies directed against the pro region of the TGF-.beta. precursor. Further, this invention provides a pharmaceutical composition comprising the pro region of the TGF-.beta. precursor. Also, this invention provides methods for diagnosing, detecting and treating subjects suffering from disorders associated with TGF-.beta.3.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.