Method for obtaining bone marrow free of tumor cells using transforming growth factor .beta.3
US5262319A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 25, 1990 |
| Grant date | Nov 16, 1993 |
| Priority date | — |
| Expiry date | Jun 25, 2010 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/495
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides (1) an antibody which (a) specifically binds to human TGF-.beta.3 and (b) exhibits substantially no cross reactivity with TGF-.beta.1 or TGF-.beta.2 and (2) antibodies directed against the pro region of the TGF-.beta. precursor. Further, this invention provides a pharmaceutical composition comprising the pro region of the TGF-.beta. precursor. Also, this invention provides methods for diagnosing, detecting and treating subjects suffering from disorders associated with TGF-.beta.3.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.