Process for the reaction of halogenated aromatics with electrophiles

US5262556A · kind A · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Bernard Riefling · Darmstadt, DE
• Jurgen Seubert · Darmstadt, DE
• Volker Reiffenrath · Roßdorf, DE
• Reinhard Hittich · Seeheim-Jugenheim, DE

Key dates

• Filing date: May 6, 1992
• Grant date: Nov 16, 1993
• Expiry date: May 6, 2012

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C09K2019/0407
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to a process for the reaction of fluorinated or chlorinated aromatics with electrophiles at the ortho position relative to the fluorine or chlorine atom, characterized in that a strong base is added to a mixture of the fluorinated or chlorinated aromatic and the electrophile.