Method and apparatus for localization of intracerebral sources of electrical activity
US5263488A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 5, 1992 |
| Grant date | Nov 23, 1993 |
| Priority date | — |
| Expiry date | Oct 5, 2012 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06F2218/22
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Signals from plural electrodes placed at known positions on the head of an individual are digitized and processed in a computer processor which includes a bank of spatial filters. The filters are designed to meet a linearly constrained minimum variance criterion so that they each substantially pass signal energy from a location within the brain known with respect to the electrodes while rejecting signal energy from other locations within the brain. The outputs of the filters can be used to estimate the signal power at each of the locations in the brain, or the dipole moment at each location, and this information can be displayed on a display device to provide a map of source activity within the brain. The spatial filters do not require prior knowledge of the number of sources, and the number of discrete sources can be identified as well as the location, power, and dipole moment of the sources. This information can be used when a stimulus is applied to the individual to determine the regions of the brain which respond to the stimulus, or to localize neural activity in the brain to identify the location of pathology within the brain.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.