Detection of basement membrane components as diagnostic of cancer and other diseases
US5264370A · kind A · utility
2Cited by
10References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 26, 1991 |
| Grant date | Nov 23, 1993 |
| Priority date | — |
| Expiry date | Jun 26, 2011 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/6887
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods for the diagnosis of diseases that result in the release of fragments of basement membrane, including fragments, intact molecules and/or complexes of basement membrane components, are disclosed. Detection of basement membrane fragments, intact molecules and/or complexes in a biological fluid by the immunological and physicochemical methods of the present invention allows the diagnosis of a variety of diseases, including cancers, collagen degenerative diseases, and hepatitis. Suitable biological fluids include urine, serum, synovial fluid, and cerebrospinal fluid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.