Polycyclic conjugates
US5264431A · kind A · utility
10Cited by
3References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 6, 1992 |
| Grant date | Nov 23, 1993 |
| Priority date | — |
| Expiry date | Nov 6, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H15/26
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Staurosporin derivatives of the formula I are described, ##STR1## in which R.sub.1 is hydrogen, hydroxyl, lower alkoxy or oxo and R.sub.2 is a radical of the formula II ##STR2## in which the configuration of the sugar moiety is derived from D-glucose, D-galactose or D-mannose, and R.sub.3 -R.sub.7 are as defined below. These compounds have a pronounced and selective inhibitory action on the enzyme proteinkinase C and have, inter alia, an antitumor action.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.