3-aryl oxazolidinone compounds and therapeutic use thereof
US5264443A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 9, 1992 |
| Grant date | Nov 23, 1993 |
| Priority date | — |
| Expiry date | Apr 9, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D263/24
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Derivatives having the formula: ##STR1## where R.sub.1 denotes C.sub.1 -C.sub.4 alkyl; X denotes oxygen or methylene; R.sub.2 denotes C.sub.1 -C.sub.4 alkyl or CF.sub.3 ; R.sub.3 denotes a CH.sub.2 R.sub.4 group in which R.sub.4 is (i) a pentagonal or hexagonal aromatic heterocyclic group comprising one or two nitrogen atoms and optionally fused with a benzene ring or (ii) a group having the formula ##STR2## where n=0 or 1, and R.sub.5 and R.sub.6 independently denote C.sub.1 -C.sub.4 alkyl or benzyl, and R.sub.5 and R.sub.6 also, together with the nitrogen atom to which they are bonded, form a piperidino or pyrrolidino or morpholino or N-methyl piperazino radical, and their N-oxide forms and acid addition salts of these derivatives and their N-oxide forms, the derivatives being in various stereoisomeric forms or in the form of a mixture of these forms, including the racemic form.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.