Insect-specific paralytic neurotoxin genes for use in biological insect control: methods and compositions
US5266317A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 4, 1990 |
| Grant date | Nov 30, 1993 |
| Priority date | — |
| Expiry date | Oct 4, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2710/14143
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Genes encoding insect-specific paralytic neurotoxins, particularly those of insect-parasitic mites, including Pyemotes, are described. Recombinant DNA molecules in which the neurotoxin coding sequences are placed under the control of heterologous promoters are also described. Such molecules are useful for the development of biological insect control agents which produce insect-toxic levels of the neurotoxin. Specifically described are genetically altered baculoviruses which produce insect-specific paralytic neurotoxins and which display improved toxic effect on insects. Insect-toxic compositions are also provided. Methods of insect control using these neurotoxin genes, methods for production of neurotoxins in cells, and methods of production of insect control agents are described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.