In situ modification of alginate
US5266326A · kind A · utility
102Cited by
3References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 30, 1992 |
| Grant date | Nov 30, 1993 |
| Priority date | — |
| Expiry date | Jun 30, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A method of modifying salts of alginic acid in situ for prevention and treatment of various intra-articular and extra-articular (spine) complications modifies the alginate in situ to an insoluble gel. This in situ modification provides a final product which can be compressed within the intra-articular space thus remaining localized. The modified material can have varied mechanical strengths and thus varied degradation times and can serve as a matrix for localizing and slowly releasing therapeutic agents. The modified material is biocompatible and biodegradable, thus requiring no reoperation for removal.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.