DNA vector and recombinant host cell for production of hirullin P6 and P18
US5268296A · kind A · utility
8Cited by
7References
3Claims
0Family size
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Key dates
| Filing date | Feb 21, 1992 |
| Grant date | Dec 7, 1993 |
| Priority date | — |
| Expiry date | Feb 21, 2012 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/942
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel polypeptides, designated hirullins, have a strong antithrombic activity and can therefore be used for the therapy and prophylaxis of thromboses. Said compounds are isolated from the leech Hirudinaria manillensis or are produced by conventional peptide synthesis or by recombinant DNA techniques. DNA sequences encoding hirullins P6 and P18 are supplied, hybrid vectors and transformed microorganisms for recombinant hirullin production are supplied.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.