Vectors and compounds for expression of zymogen forms of human protein C
US5270178A · kind A · utility
17Cited by
1References
25Claims
0Family size
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Inventors
Key dates
| Filing date | Feb 23, 1990 |
| Grant date | Dec 14, 1993 |
| Priority date | — |
| Expiry date | Feb 23, 2010 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/143333
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for the recombinant production of zymogen forms of human protein C is described. These zymogen forms differ from native zymogen protein C in their increased sensitivity to activation by thrombin and thrombin/thrombomodulin. DNA compounds, vectors, and transformants useful in the method are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.