Method for sequencing DNA base pairs
US5270214A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 30, 1990 |
| Grant date | Dec 14, 1993 |
| Priority date | — |
| Expiry date | May 30, 2010 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/143333
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The base pairs of a DNA structure are sequenced with the use of a scanning tunneling microscope (STM). The DNA structure is scanned by the STM probe tip, and, as it is being scanned, the DNA structure is separately subjected to a sequence of infrared radiation from four different sources, each source being selected to preferentially excite one of the four different bases in the DNA structure. Each particular base being scanned is subjected to such sequence of infrared radiation from the four different sources as that particular base is being scanned. The DNA structure as a whole is separately imaged for each subjection thereof to radiation from one only of each source.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.