Patent · US Expired

Fluorinated hydroxyalkylquinoline acids as leukotriene antagonists

US5270324A · kind A · utility

24Cited by
5References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 10, 1992
Grant dateDec 14, 1993
Priority date
Expiry dateApr 10, 2012

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P43/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Compounds having the formula I: ##STR1## are leukotriene antagonists and inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.