Patent · US Expired

Cholesteral lowering agents

US5270332A · kind A · utility

3Cited by
5References
7Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 21, 1992
Grant dateDec 14, 1993
Priority date
Expiry dateAug 21, 2012

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D493/08
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

This invention relates to compounds of structural formula (I): ##STR1## which are squalene synthase inhibitors and thus useful as cholesterol lowering agents. The compounds also exhibit antifungal activity and are inhibitors of farnesyl-protein transferase.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.