Detection of Alzheimer's disease and other diseases using a photoaffinity labeling method
US5272055A · kind A · utility
17Cited by
3References
15Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Dec 24, 1991 |
| Grant date | Dec 21, 1993 |
| Priority date | — |
| Expiry date | Dec 24, 2011 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/811
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method for diagnosing a neurological disease comprising detecting a neurological disease-specific biochemical marker macromolecule within a sample of extracted cerebral spinal fluid is disclosed. In particular, a radioactively labeled photoaffinity probe is used to diagnose a neurological disease. For instance, Alzheimer's disease can be diagnosed by detecting a disease-specific protein having a molecular weight of about 42,000 daltons, i.e., glutamine synthetase.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.