Cluster conjugates of drugs with antibodies
US5272253A · kind A · utility
20Cited by
5References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 1, 1991 |
| Grant date | Dec 21, 1993 |
| Priority date | — |
| Expiry date | Jul 1, 2011 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Targeted drug conjugates which enable a large number of molecules of drug to be directed to a cell by a single molecule of antibody are provided. The invention also provides intermediates for the synthesis of such conjugates and cytotoxic drugs modified in accordance with the cluster concept of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.