Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer
US5273760A · kind A · utility
434Cited by
5References
34Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 24, 1991 |
| Grant date | Dec 28, 1993 |
| Priority date | — |
| Expiry date | Dec 24, 2011 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/5078
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A stabilized solid controlled release dosage form having a coating derived from an aqueous dispersion of ethylcellulose is obtained by overcoating a substrate including a therapeutically active agent with an aqueous dispersion of ethylcellulose and then curing the coated substrate at a temperature and relative humidity elevated to a suitable level above ambient conditions until the coated dosage form attains a stabilized dissolution profile substantially unaffected by exposure to storage conditions of elevated temperature and/or elevated relative humidity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.