Recombinant human cytomegalovirus containing foreign gene
US5273876A · kind A · utility
31Cited by
1References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 16, 1990 |
| Grant date | Dec 28, 1993 |
| Priority date | — |
| Expiry date | Oct 16, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/16064
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a virus comprising a DNA sequence essential for replication of a human cytomegalovirus and at least one foreign DNA sequence adapted for expression in a host. The foreign DNA sequence may encode a human immunodeficiency virus anti-sense mRNA sequence or an antigenic polypeptide, e.g., a malarial surface antigen. Also provided are therapeutic compositions and vaccines which comprise the novel viruses of the present invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.