Gamma-iterferon-leukotoxin gene fusions and uses thereof
US5273889A · kind A · utility
16Cited by
17References
11Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Oct 16, 1991 |
| Grant date | Dec 28, 1993 |
| Priority date | — |
| Expiry date | Oct 16, 2011 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/811
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
New chimeric proteins, DNA encoding the same, and the use of these proteins in stimulating immunity against respiratory diseases such as pneumonia, including shipping fever pneumonia, are disclosed. The chimeric proteins include at least one epitope of leukotoxin fused to an active fragment of a cytokine. The chimeric proteins can be used in a vaccine composition. Also disclosed are methods of vaccination as well as methods of making the proteins employed in the vaccines.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.